Status:
UNKNOWN
Project Arthritis Recovering Quality of Life Through Education 70+
Lead Sponsor:
University of Sao Paulo General Hospital
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
70+ years
Phase:
NA
Brief Summary
Introduction: Quadriceps weakness was previously associated with functional impairment of osteoarthritis (OA). Evidence also suggests that muscle strength may prevent the progression of existing OA. I...
Detailed Description
Osteoarthritis (OA) is the most common form of arthritis, affecting mainly women. Patients with OA present pain that usually worsens with weight support and improves with rest, as well as morning stif...
Eligibility Criteria
Inclusion
- Men and women diagnosed with OAJ with or without metabolic syndrome (ie at least two of: overweight / obese, hyperglycemia, dyslipidemia, hypertension)
- Age greater than or equal to 70 years.
- Classified as degrees I to III of Kelgreen and Lawrence (K-L), that is, any degree of gonarthritis without obliteration of joint space.
- Indication of clinical treatment of OA
- Patients without disabsorbing syndrome or inflammatory diseases of the gastrointestinal tract (GIT).
- Patients not undergoing gastroplasty or surgery that altered the transit of food in the TGI (Roux "Y", for example).
- Patients with creatinine clearance greater than 60 ml / min / 1.73m2
- Patients not submitted to previous arthroplasty in the lower limbs.
- Patients not submitted to infiltration in the knees up to 6 months before the study.
- Patients with no personal history of cognitive, psychiatric and / or neurological disorders, whose symptoms presented at the time of evaluation are related or significantly interfere with the functions of attention, memory, logical reasoning, comprehension, in order to impair the assimilation of the given guidelines.
- Ability to read, understand and respond to the questionnaires
Exclusion
- Missing the schedules and not performing the tasks as performed by the professionals.
- Patients who develop allergy or intolerance to creatine, dextrose or BCAA during the study.
Key Trial Info
Start Date :
August 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 15 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04058002
Start Date
August 15 2019
End Date
October 15 2020
Last Update
August 15 2019
Active Locations (1)
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1
Instituto de Ortopedia e Traumatologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, Brazil, 05403-010