Status:
UNKNOWN
Glycocalyx Levels in Patients Undergoing Pancreatectomy
Lead Sponsor:
University of Malaya
Conditions:
Endothelial Degeneration
Pancreatic Cancer
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
Background: On the surface of every healthy cellular membrane resides a layer known as the glycocalyx. This structure consists of extracellular domains of receptor, adhesion and transmembrane molecul...
Detailed Description
This is a prospective study that will be conducted in the Main Operating theatres of UMMC on patients with pancreatic cancer undergoing elective pancreatectomy (includes all forms of pancreatectomy su...
Eligibility Criteria
Inclusion
- ASA 1-3
- patients aged between 18-75 years old with written informed consent
Exclusion
- Patients who refuse to participate,
- Have severe congestive heart failure (NYHA class III/IV) or severe respiratory disease (PaO2/FiO2 \< 200),
- Suffer significant renal or hepatic dysfunction (creatinine raised \>50 % or liver enzymes \>50 % of normal values),
- Pregnant
- Allergic to gelofusine and human albumin
Key Trial Info
Start Date :
August 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04058236
Start Date
August 15 2019
End Date
July 31 2021
Last Update
April 30 2020
Active Locations (1)
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1
Anaesthesia Department, Faculty of Medicine, University Malaya
Kuala Lumpur, Kuala Lumpur, Malaysia, 59100