Status:

COMPLETED

MUSE Study to Evaluate the Pharmacokinetics, Safety and Tolerability of S6G5T-3

Lead Sponsor:

Sol-Gel Technologies, Ltd.

Conditions:

Acne Vulgaris

Eligibility:

All Genders

9+ years

Phase:

PHASE1

Brief Summary

To assess the degree of systemic exposure of S6G5T-3 compared to the Reference Listed Drug (RLD) Retin-A® 0.1% Cream when applied topically once daily for 14 days, under maximal use conditions in adol...

Eligibility Criteria

Inclusion

  • Male and female subjects 9 years of age or older.
  • Subject must consent to participate, verified by signing an approved written Informed Consent Form (ICF).
  • Subjects must be generally healthy and free from any clinically significant disease, other than acne vulgaris, that might interfere with the study evaluations
  • All females of child-bearing potential and premenarchal, excluding women who are surgically sterile

Exclusion

  • Acne conglobata, acne fulminans, secondary acne (chloracne, drug-induced acne etc.) or severe acne requiring systemic treatment.
  • Underlying disease which requires the use of topical or systemic therapy which may confound study results or make results difficult to interpret.;
  • Subjects unable to communicate well with the site study team (i.e., language problem, poor mental development or impaired cerebral function).
  • Any other factor that, in the opinion of the Investigator, would prevent the subject from complying with the requirements of the protocol.

Key Trial Info

Start Date :

June 27 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 6 2020

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT04059523

Start Date

June 27 2019

End Date

February 6 2020

Last Update

March 18 2020

Active Locations (2)

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Page 1 of 1 (2 locations)

1

DermResearch, Inc.

Austin, Texas, United States, 78759

2

J&S Studies, Inc

College Station, Texas, United States, 77845