Status:
COMPLETED
Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammacheck™) in Patients With Interstitial Lung Disease, Lung Cancer and Healthy Volunteers.
Lead Sponsor:
Portsmouth Hospitals NHS Trust
Conditions:
Interstitial Lung Disease
Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
A cross-sectional study of EBC H2O2 levels, as measured by a novel device, 'Inflammacheck™', and other markers of disease severity in patients with ILD and Lung Cancer.
Detailed Description
Inflammation and oxidative stress are processes that occur early in the disease process within both ILD and lung cancer. Current tools for assessing inflammation and oxidative stress, such as fibre-op...
Eligibility Criteria
Inclusion
- Male or Female, aged ≥18 years.
- A confirmed, clinician made diagnosis of Interstitial Lung Disease (ILD) supported by evidence of ILD on a CT chest scan recorded at any time.
- OR a clinician suspected or confirmed Lung Cancer, with or without asthma and/or COPD
- OR a healthy volunteer with no known history of lung disease (defined as no current clinical diagnosis of, or be receiving treatment for, a lung disease).
- Willing and able to give informed consent for participation in the study.
Exclusion
- Existing co-morbidities that may prevent them from performing spirometry or other study measurements (at the discretion of the clinical investigator).
- Known other lung, chest wall, neuromuscular, or cardiac disease or abnormality (including end-stage disease or cancer) that would confound symptom scores and spirometry.
- In the opinion of the clinical investigator, participant could be put at risk of harm by having to perform any of the study procedures.
- Unable to comprehend the study and provide informed consent, e.g. insufficient command of English in the absence of someone to adequately interpret.
Key Trial Info
Start Date :
October 30 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 14 2019
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT04061356
Start Date
October 30 2018
End Date
September 14 2019
Last Update
April 7 2023
Active Locations (1)
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1
Portsmouth Hospitals NHS Trust
Portsmouth, Hampshire, United Kingdom, PO6 3LY