Status:

WITHDRAWN

Ultrasound and CT to Measure Muscle in Hip OA

Lead Sponsor:

University of Maryland, Baltimore

Conditions:

Hip Osteoarthritis

Eligibility:

All Genders

60-85 years

Brief Summary

This study will examine alterations in muscle in individuals with hip osteoarthritis compared to individuals without hip arthritis. All individuals will receive imaging of their hip and low back muscl...

Detailed Description

Hip osteoarthritis (OA) is one of the most common causes of disability in older adults, with pain, stiffness, and weakness the most frequently reported symptoms. Weakness is a major concern as decreas...

Eligibility Criteria

Inclusion

  • Age \>=60 and \<= 85
  • Hip OA group ONLY: Diagnosed unilateral OA of the hip as determined by Kellgren/Lawrence (K/L) or similar grades of 2, 3, or 4 from standard hip series A-P radiographs.
  • CONTROL GROUP ONLY: No significant OA of either hip joint as determined by K/L grades or similar of 0 or 1 from standard hip series A-P radiographs.

Exclusion

  • BMI\>35
  • Other significant orthopedic conditions of the hip, pelvis or lumbar spine, including prior trauma or significant surgical procedures (examples: lumbar fusion, fractures with surgical management, hip joint replacement, etc.)
  • Diagnosis of any other arthritic conditions other than osteoarthritis (e.g. psoriatic arthritis or rheumatoid arthritis, ankylosing spondylitis/spondylosis).
  • Any known neurological disorders, including multiple sclerosis, stroke, spinal cord injury or any serious medical condition that may affect muscle quality.
  • Inability to undergo CT testing for any reason
  • Significant cardiovascular conditions that would make the participant unsafe for any testing procedures (for example uncontrolled hypertension (BP\>160/100 at rest), uncontrolled arrhythmia, uncontrolled diabetes, etc.)

Key Trial Info

Start Date :

December 4 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 29 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04061499

Start Date

December 4 2019

End Date

April 29 2021

Last Update

May 4 2021

Active Locations (1)

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1

Baltimore VA Medical Center

Baltimore, Maryland, United States, 21201