Status:
UNKNOWN
Interaction Between HIV and Platelets
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
HIV Seropositivity
Eligibility:
All Genders
18+ years
Brief Summary
The investigators propose that the lack of immune response in InR is driven by HIV-containing platelets that might interact with macrophages and CD4+ T-cells although by different mechanisms. In the o...
Detailed Description
The investigators have recently shown that infectious HIV is carried by platelets in the blood of HIV-infected patients which failed to respond immunologically to cART despite viral suppression (Immun...
Eligibility Criteria
Inclusion
- For all patients:
- aged ⩾ 18 years;
- patients who can read and understand information document.
- For VIH positive patients without lymphoma:
- VIH positive patients with negative or positive viral load under cART since 1 year;
- patient under cART.
- For VIH positive patients with lymphoma:
- VIH positive patient with negative viral load under cART since 1 year;
- patient with lymphoma.
- For Healthy Volunteers:
- VIH negative patient (control) already included in clinical trial;
- patient major without haematological pathology.
Exclusion
- patient \< 18 years;
- Unable to read and understand information document.
Key Trial Info
Start Date :
April 17 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT04062825
Start Date
April 17 2020
End Date
March 1 2025
Last Update
March 17 2023
Active Locations (1)
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1
Service Hématologie Immunologie, Hôpital Ambroise Paré
Boulogne-Billancourt, France, 92100