Status:

ENROLLING_BY_INVITATION

The Use of Focused Ultrasound and DCE K-trans Imaging to Evaluate Permeability of the Blood-Brain Barrier

Lead Sponsor:

Neurological Associates of West Los Angeles

Conditions:

Low Grade Glioma of Brain

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The limitation of treating intrinsic brain pathologies has been circumvented with neurosurgical techniques; however, less invasive approaches may be desirable particularly for widespread or multifocal...

Detailed Description

Treatment of intrinsic brain diseases is challenging because brain barrier (BBB) limits the delivery of drugs, particulates and cellular elements such as stem cells to the central nervous system (CNS)...

Eligibility Criteria

Inclusion

  • Subjects undergoing routine, repetitive MRI scanning for monitoring low grade gliomas
  • 18 or older

Exclusion

  • • Cognitive decline with mild cognitive impairment (Clinical Dementia Rating stage 0.5) through moderate dementia CDR stages 1 and 2

Key Trial Info

Start Date :

June 11 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 20 2027

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04063514

Start Date

June 11 2021

End Date

January 20 2027

Last Update

March 24 2023

Active Locations (1)

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1

Neurological Associates of West LA

Santa Monica, California, United States, 90403