Status:

COMPLETED

Vivio AS (Aortic Stenosis) Detection Study

Lead Sponsor:

Avicena LLC

Conditions:

Aortic Stenosis

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

Evaluate the sensitivity and specificity of the Vivio System when used as an aid in the identification of heart sounds associated with severe aortic stenosis.

Detailed Description

Prospective, non-randomized, multi-center study of adult subjects referred for echocardiography. Total of 200 enrolled subjects at 3 sites. Up to 10 roll-in subjects per site. Enrolled subjects will u...

Eligibility Criteria

Inclusion

  • Adult subjects (21 years of age or older).
  • Referred for transthoracic echocardiography by physician/primary care provider/cardiologist.
  • Willing and able to participate in all study evaluations and allow access to medical testing and records.
  • Signed informed consent or have a legally authorized representative who provides informed consent on behalf of the subject.

Exclusion

  • Acute coronary syndrome, cardiogenic shock or the need for inotropic/mechanical circulatory support.
  • Need for bedside echocardiogram (inpatient).
  • Prosthetic device previously implanted at aortic valve position.
  • Inability to palpate carotid pulse (e.g. due to severe obesity)
  • History of carotid sinus hypersensitivity (i.e. fainting in response to touching or positioning the neck).
  • History of carotid artery disease or treatment (e.g. unstable carotid plaques that might rupture upon massage or endarterectomy).
  • Open skin lesions at target site of electronic stethoscope/Vivio device examination.

Key Trial Info

Start Date :

April 2 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 29 2019

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04066634

Start Date

April 2 2019

End Date

October 29 2019

Last Update

August 2 2021

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Morristown Medical Center

Morristown, New Jersey, United States, 07960

2

St. Francis Hospital

Roslyn, New York, United States, 11576

3

Miriam Hospital

Providence, Rhode Island, United States, 02906