Status:

COMPLETED

Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol Value

Lead Sponsor:

McMaster University

Conditions:

Alcohol Use Disorder

Alcohol Drinking

Eligibility:

All Genders

21-55 years

Phase:

NA

Brief Summary

This study uses techniques from an area of research known as neuroeconomics, which integrates concepts and methods from psychology, neuroscience, and economics to better understand how people make dec...

Detailed Description

Neuroeconomics integrates concepts and methods from psychology, economics, and cognitive neuroscience to understand the neurobiological foundations of decision making, and has been increasingly applie...

Eligibility Criteria

Inclusion

  • 21-55 years old;
  • Right-handed;
  • Fluent English speaker;
  • Heavy drinker (i.e., on average \> 14/7 drinks per week for males/females in past three months;
  • Average of 1 heavy drinking episode weekly (heavy drinking episode = 5+/4+ for males/females) over past three months

Exclusion

  • Currently receiving treatment, or seeking treatment, for alcohol related problems;
  • Current Diagnostic and Statistical Manual (DSM-5) substance use disorder other than alcohol or tobacco;
  • Weekly or more frequent use of recreational drugs;
  • History of schizophrenia-spectrum disorders, psychotic disorders, bipolar disorder, or PTSD;
  • History of neurocognitive disorder or impairment;
  • MRI contraindications (e.g., metal in body, history of seizure, etc.);
  • History of serious brain injury;
  • Currently taking psychotropic medications or medications that could affect cerebral blood flow;
  • Pregnancy (females);
  • Attending any study session with a positive breath alcohol concentration (BrAC \> 0.00g%)

Key Trial Info

Start Date :

January 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT04067765

Start Date

January 1 2020

End Date

December 31 2023

Last Update

September 9 2025

Active Locations (1)

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1

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada, L8N3K7