Status:
UNKNOWN
Impact of Ischemic Post-conditioning
Lead Sponsor:
Assiut University
Conditions:
ST Elevation Myocardial Infarction
Ventricular Remodeling
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Study will investigate \& compare the left ventricular remodeling \& systolic function between two groups of ST-elevation myocardial infarction undergoing primary per-cutaneous coronary intervention a...
Detailed Description
Among re-perfusion strategies for the management of ST-elevation myocardial infarction , primary per-cutaneous coronary intervention is the preferred one within 120 minutes from the first medical cont...
Eligibility Criteria
Inclusion
- Patients presenting with symptoms of acute myocardial ischemia with time of symptom onset \< 12 hours \& meeting the other following criteria of type 1 myocardial infarction according to the fouth universal definition of myocardial infarction(Thygesen, 2019):
- Detection of a rise and/or fall of cardiac troponin values with at least one value above the 99th percentile upper reference limit.(URL)
- Ischemic ECG changes; New or persistent ST-segment elevation with development of pathological Q waves
- Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality in a pattern consistent with an ischemic etiology.
- Patients undergoing primary percutaneous coronary intervention as the first choice of revascularization therapy.
Exclusion
- Patients with transient ST segment elevation in the surface electrocardiography.
- Patients presenting within \> 12 hours from the onset of maximal symptoms.
- Patients with evidence of pre-infarction angina.
- Patients with evidence of collateral blood flow to the infarct region on their angiogram.
- Patients with history of old myocardial infarction causing chronic impairment of LV systolic function.
- Patients presenting with ST-segment elevation myocardial infarction other than type 1 according to the fouth universal definition of myocardial infarction
Key Trial Info
Start Date :
October 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 15 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04068116
Start Date
October 15 2019
End Date
October 15 2021
Last Update
September 6 2019
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