Status:

UNKNOWN

Docosahexaenoic Acid (DHA) Supplementation in High Risk Pregnancies

Lead Sponsor:

Walter Reed National Military Medical Center

Collaborating Sponsors:

National Institutes of Health (NIH)

DSM Nutritional Products, Inc.

Conditions:

Inflammation

Pregnancy Related

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Purpose: Determine the effects of maternal docosahexaenoic acid (DHA) supplementation during pregnancy on levels of DHA, synaptamide (novel anti-inflammatory metabolite), and inflammatory biomarkers d...

Detailed Description

All pregnant women meeting the inclusion/exclusion criteria will be identified at the time of their regular OB appointments between the 8th and the 14th week of pregnancy (+/- 3 days) Research team me...

Eligibility Criteria

Inclusion

  • regnant female military health care beneficiaries ≥18 years of age
  • Between the 8th and 14th week of pregnancy at enrollment
  • BMI of ≥30.0 kg/m2 and/or history of previous preterm delivery at \<36 weeks gestation
  • Planning to deliver at WRNMMC
  • DEERS-eligible
  • All infants born to mothers enrolled in this study who do not meet any exclusion criteria

Exclusion

  • Routine use of DHA supplement (including DHA containing prenatal vitamins) and/or fish consumption greater than twice per week
  • Women with a fish allergy
  • Known major fetal anomaly believed to be lethal
  • Maternal treatment for clotting disorder
  • Allergy to corn or soybean oils

Key Trial Info

Start Date :

February 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2020

Estimated Enrollment :

210 Patients enrolled

Trial Details

Trial ID

NCT04069195

Start Date

February 1 2019

End Date

December 1 2020

Last Update

August 28 2019

Active Locations (1)

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Walter Reed National Miltiary medical center

Bethesda, Maryland, United States, 20889