Status:

COMPLETED

Safety and Immunogenicity Study of QIVc in Healthy Pediatric Subjects

Lead Sponsor:

Seqirus

Conditions:

Influenza

Human

Eligibility:

All Genders

6-47 years

Phase:

PHASE3

Brief Summary

This phase 3 clinical study is a randomized, observer-blind, comparator-controlled, multicenter study of QIVc versus a US-licensed comparator QIV in children 6 months through 47 months of age. The pur...

Eligibility Criteria

Inclusion

  • Individuals of 6 through 47 months of age on the day of informed consent.
  • Individuals whose parent(s)/Legally Acceptable Representative (LAR) have voluntarily given written informed consent after the nature of the study has been explained according to local regulatory requirements, prior to study entry.
  • Individuals who can comply with study procedures including follow-up
  • Individual is in generally good health as per the Investigator's medical judgement

Exclusion

  • Acute (severe) febrile illness
  • History of any anaphylaxis, serious vaccine reactions or hypersensitivity, including allergic reactions, to any component of vaccine or medical equipment whose use is foreseen in this study
  • A known history of Guillain-Barre Syndrome or other demyelinating diseases such as encephalomyelitis and transverse myelitis
  • Any other clinical condition that, in the opinion of the investigator, might interfere with the results of the study or pose additional risk to the subject due to participation in the study
  • Received influenza vaccination or has had documented influenza disease in the last 6 months prior to informed consent.

Key Trial Info

Start Date :

September 6 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 3 2020

Estimated Enrollment :

2414 Patients enrolled

Trial Details

Trial ID

NCT04074928

Start Date

September 6 2019

End Date

September 3 2020

Last Update

January 12 2022

Active Locations (47)

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Page 1 of 12 (47 locations)

1

84035 CCR Research

Mobile, Alabama, United States, 36608

2

84040 Southland Clnical Research Center

Anaheim, California, United States, 92804

3

84044 Premier Health Research Center

Downey, California, United States, 90240

4

84028 Orange County Research Institute

Ontario, California, United States, 91763