Status:
COMPLETED
INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers
Lead Sponsor:
Arizona State University
Conditions:
Dehydration
Diabetes Mellitus, Type 2
Eligibility:
All Genders
30-55 years
Phase:
NA
Brief Summary
Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation....
Eligibility Criteria
Inclusion
- healthy sedentary participants
- aged 30-55 years
- body mass 27.5-35.0 kg·m2
- low water intake less than 1.5 L∙day-1 (male) or 1.0 L∙day-1 (female)
- 24 h urine osmolality greater than 800 mmol/kg
Exclusion
- diabetes HbA1c \>6.5%
- impaired liver or kidney function
- cardiovascular disease
- weight change of more than 3 kg in the past month
- pregnancy
- previous surgery on digestive tract
- exercise \>4 h/week
Key Trial Info
Start Date :
September 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2019
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04076995
Start Date
September 18 2019
End Date
December 19 2019
Last Update
February 11 2020
Active Locations (1)
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1
Arizona Biomedical Collaborative
Phoenix, Arizona, United States, 85004