Status:
WITHDRAWN
Memory-Updating Technique to Reduce Food Craving and High Calorie Food Intake Among Individuals With Overweight/Obesity
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Overweight
Obesity
Eligibility:
All Genders
18-59 years
Phase:
NA
Brief Summary
This study will evaluate the effects of retrieval-extinction (R-E) training on responding to high calorie foods including self-report craving, physiological responding, and high calorie food intake in...
Detailed Description
Participants (N=150) with overweight/obesity (body mass index ≥25.0 kg/m\^2) will be recruited locally via media outlets, flier postings, and local research registries to participate in a novel labora...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Age 18-59 years
- Body mass index ≥25.0, indicating overweight/obesity
- Interested in losing weight
- Adequate liking of ≥4 foods to be presented during extinction training
- Willing to complete the following necessary study procedures: (1) eat study foods during taste test, (2) have heart rate sensors placed on skin, (3) abstain from alcohol, cannabis, benzodiazepines, opiates, or other illegal substances starting at midnight before each session, (4) attend sessions at the same time each day and starting with Session 1 on a Monday or Tuesday, and (5) abstain from consuming high calorie foods/drinks across the first 4 sessions
- EXCLUSION CRITERIA:
- Engaged in a weight loss treatment/program or involved in another research study providing treatment/intervention for weight loss
- Participation in a food cue-reactivity pilot study that used procedures similar to those of the current study (e.g., food cue-reactivity task, bogus taste test)
- Diabetes diagnosis
- Initiation of thyroid-related medications or, for women, initiation of new birth control medication, an implant, or intrauterine device in the past 3 months
- Regular use of benzodiazepines (i.e., \>5 times in the past 30 days)
- Use of weight- or appetite-affecting medication
- Currently receiving treatment for an eating disorder
- Bariatric surgery in the past 3 years
- Food allergies or restrictions over the next 4 months preventing consumption of foods presented during lab tasks
- Has a pacemaker implant
- For women: currently pregnant or planning to become pregnant in the next 4 months
- For women: currently breastfeeding with \>50% of baby's/child's nutrition coming from breast milk
Exclusion
Key Trial Info
Start Date :
October 2 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 2 2020
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04077385
Start Date
October 2 2020
End Date
October 2 2020
Last Update
January 26 2021
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213