Status:
COMPLETED
Shifting Away From Pain: a Neurocognitive Approach in Treatment of Whiplash
Lead Sponsor:
University Ghent
Collaborating Sponsors:
Research Foundation Flanders
Conditions:
Whiplash Injuries
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The broad aim of this study is to investigate the effect of a modern neuroscience approach, which combines education on pain neuroscience with cognition-targeted exercise therapy and stress management...
Detailed Description
This project runs in parallel to a larger randomized-controlled trial (RCT) in which the 'modern neuroscience approach to WAD' is compared to usual care evidence-based physiotherapy (clinical trial re...
Eligibility Criteria
Inclusion
- CWAD group:
- Experienced a whiplash trauma which is at least 3 months old and causes pain since at least 3 months, with pain experience with a mean pain frequency of 3 or more days per week, and with self-reported moderate to severe pain-related disability, established by a score of 15 or more of a maximum of 50 on the Neck Disability Index
- Patients classified as WAD II or WAD III on the modified Quebec Task Force Scale
- Native Dutch speaker
- Not starting new treatments or medication and continuing their usual care 6 weeks prior to and during study participation (to obtain a steady state)
- Refraining from consuming caffeine, alcohol and nicotine in the hour before the MRI scans (in both measurement times: before the start of the rehabilitation and after the end of the rehabilitation).
Exclusion
- Neuropathic pain
- Being pregnant or having given birth in the preceding year
- Chronic fatigue syndrome
- Fibromyalgia
- Cardiovascular disorders
- Epilepsy
- Endocrinological disorders
- Rheumatic disorders
- Psychiatric disorders
- History of neck surgery
- Loss of consciousness during/after the whiplash trauma
- MRI incompatible health condition (e.g., pacemaker, metal prosthetic devices)
- Psychiatric condition and ongoing medication that would alter emotional or sensory processing
- Claustrophobia.
- Healthy volunteers: (matched for age and gender). Additional exclusion criteria include for healthy volunteers
- a history of a chronic pain syndrome
- a pain condition in the last six months for which treatment was sought
Key Trial Info
Start Date :
September 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2022
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT04077619
Start Date
September 4 2019
End Date
October 1 2022
Last Update
November 15 2022
Active Locations (1)
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1
Department of rehabilitation sciences (Ghent University)
Ghent, Belgium, 9000