Status:
COMPLETED
Influence of Proteins on the Bioavailability of Carotenoids
Lead Sponsor:
Luxembourg Institute of Health
Collaborating Sponsors:
Laboratoires Réunis
Université Catholique de Louvain
Conditions:
Absorption; Chemicals
Healthy Diet
Eligibility:
MALE
20-50 years
Phase:
NA
Brief Summary
A postprandial intervention study is conducted on healthy male subjects to evaluate whether the addition of proteins (why protein isolate, soy protein) can help to increase the bioavailability of caro...
Detailed Description
Participants who agree to sign the Informed Consent Form and are considered eligible for participation will be scheduled for a first and brief screening visit enrolment visit) to collect a spot urine ...
Eligibility Criteria
Inclusion
- healthy and free living;
- men;
- age between 20 and 50 years old;
- Body-Mass-Index (BMI) \<30 kg/m2
- non-smokers (abstinent for more than 2 years);
Exclusion
- suffering from any metabolic disease that may cause digestive disturbances (such as Crohn's disease or colitis);
- malabsorption disorders;
- BMI over 30 kg/m2;
- hyperlipidaemia (triglycerides and total cholesterol over 200 mg/dl)
- any individuals following a special diet that is not compatible with wash-out periods or test meals (vegetarian, gluten-free or diabetic);
- regular consumption of more than 5 portions (80-100 g) of fruits and vegetables per day;
- being on medical treatment or consuming any medication for chronic conditions or recent illness (e.g. antibiotics);
- consuming regularly dietary supplements;
- abnormally high or low values of plasma circulating carotenoids;
- tobacco smoking;
- frequent alcohol consumption (over 2 glasses per day);
- food allergies or intolerances that are not compatible with test meals (e.g. gluten or milk intolerance);
- daily practice of intense physical activity of 120 min or more.
- No special population group such as prisoners, children, the mentally disabled or groups whose ability to give voluntary informed consent may be in question, will be recruited for this study.
Key Trial Info
Start Date :
October 11 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04078646
Start Date
October 11 2019
End Date
June 30 2021
Last Update
September 23 2021
Active Locations (1)
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1
Luxembourg Institute of Health
Strassen, Luxembourg, 1445