Status:
COMPLETED
Optimal Antibiotics for Operated Diabetic Foot Infections
Lead Sponsor:
Balgrist University Hospital
Conditions:
Diabetic Foot Infection
Surgical Wound
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
Diabetic foot problems, especially infections (DFI), require multiple resources including iterative surgeries and amputations, long-lasting antibiotic therapies, education, off-loading and eventually ...
Detailed Description
Trial 1: At enrollment (Day 1), the investigator will prescribe empiric antibiotic treatment based on instructions provided in the protocol and determine the most appropriate route of administration (...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Diabetic foot infections or ischemia/necrosis with surgical amputation/disarticulation level in vicinity of MRI signs of infection
- At least two months of follow-up from hospitalization
- Patient signing to participate, including acceptance of local wound care, -off-loading and arterial re-vascularization (if clinically indicated).
Exclusion
- At least 5 cm of distance between amputation level and infection.
- Any concomitant infection requiring more than 5 days of systemic antibiotic therapy
- Eventual osteosynthesis material not removed
Key Trial Info
Start Date :
September 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2025
Estimated Enrollment :
643 Patients enrolled
Trial Details
Trial ID
NCT04081792
Start Date
September 4 2019
End Date
March 1 2025
Last Update
June 17 2025
Active Locations (1)
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1
Balgrist University Hospital
Zurich, Canton of Zurich, Switzerland, 8008