Status:
COMPLETED
Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride
Lead Sponsor:
University of Edinburgh
Conditions:
Bicuspid Aortic Valve
Thoracic Aortic Aneurysm
Eligibility:
All Genders
20-100 years
Brief Summary
Patients with bicuspid aortic valve-related aortopathy are at increased risk of aortic dilatation, dissection and rupture. Currently, risk stratification is largely based on aortic diameter measuremen...
Detailed Description
Bicuspid aortic valve, along with other congenital conditions affecting the aortic wall, has been associated with elastic fibre loss, decrease in size of elastic lamellae, increased collagen depositio...
Eligibility Criteria
Inclusion
- Bicuspid aortic Valve or Age-sex matched healthy volunteer
Exclusion
- Pregnancy
- eGFR \< 30
- previous aortic replacement surgery
- previous aortic valve surgery
- contrast allergy
- other reason unable to undergo MRI
Key Trial Info
Start Date :
April 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 3 2023
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT04083118
Start Date
April 1 2019
End Date
September 3 2023
Last Update
November 29 2023
Active Locations (1)
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1
University of Edinburgh
Edinburgh, United Kingdom, EH16 4SB