Status:
COMPLETED
Effect of Saturated Fat (Desi Ghee) on Gut-Liver Axis in Alcoholic Hepatitis
Lead Sponsor:
Institute of Liver and Biliary Sciences, India
Conditions:
Alcoholic Hepatitis
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The pathogenesis of the alcoholic liver disease (ALD) is a complex interplay of various etiopathological factors other than direct alcohol toxicity. These factors include inflammation \& oxidative str...
Detailed Description
Alcohol is one of the predominant causes of liver diseases and liver-related deaths worldwide. 10% of heavy drinkers consuming more than 30g /day of alcohol for 5 years develop alcoholic liver disease...
Eligibility Criteria
Inclusion
- All patients with Severe Alcoholic Hepatitis
- Aged between 18-60 years
- Having Maddrey Score of \>32
- Last Intake of alcohol from 1 day to 60days
- Patients who agree for complete alcohol abstinence from the day of enrollment
Exclusion
- Patients with-
- Maddrey Score of \<32 and \>100
- Comorbidities- Diabetes, Hypertension, Coronary Artery Disease, Chronic Kidney Disease, Hypothyroid
- Continuing Alcohol intake- Non-compliant patients
- Constipation
- On Laxatives until 1 month prior to study
- On probiotics until 1 month prior to study
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04084522
Start Date
October 1 2019
End Date
January 31 2022
Last Update
March 31 2022
Active Locations (1)
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1
Institute of Liver and Biliary Sciences
New Delhi, National Capital Territory of Delhi, India, 110070