Status:
ACTIVE_NOT_RECRUITING
Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
Lead Sponsor:
Wendie Berg
Collaborating Sponsors:
Breast Cancer Research Foundation
Conditions:
Breast Cancer Female
Breast Cancer
Eligibility:
FEMALE
30-85 years
Phase:
NA
Brief Summary
This is a prospective clinical trial that will examine if contrast-enhanced mammography substantially improves breast cancer detection compared to mammography with tomosynthesis, with minimal increase...
Detailed Description
The investigators expect to show in a prospective clinical trial that, in women with a personal history of breast cancer, contrast-enhanced mammography substantially improves breast cancer detection c...
Eligibility Criteria
Inclusion
- Asymptomatic women, ages 30-85, with a personal history of breast cancer who have had at least one routine mammogram since treatment.
Exclusion
- Women with a history of prior iodinated contrast reaction
- Women with implant(s) in the breasts to be screened (as this creates artifacts and diagnostic performance of imaging in women with implants likely does not generalize to those without implants, and the sample size with implants would be too small to infer conclusions)
- Women who have had bilateral mastectomy
- Women with a history of kidney failure or estimated glomerular filtration rate (eGFR) \< 30 mL/min
- Pregnancy or lactation
- Women actively being treated for cancer of any type with chemotherapy
- Lump or other breast symptoms
- Abnormality on prior breast imaging that is being followed.
Key Trial Info
Start Date :
October 23 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2027
Estimated Enrollment :
1647 Patients enrolled
Trial Details
Trial ID
NCT04085510
Start Date
October 23 2019
End Date
June 30 2027
Last Update
November 25 2025
Active Locations (3)
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1
Magee Womancare Passavant Cranberry
Cranberry Township, Pennsylvania, United States, 16066
2
Magee Womancare Monroeville
Monroeville, Pennsylvania, United States, 15146
3
Magee Womens Hospital
Pittsburgh, Pennsylvania, United States, 15213