Status:

COMPLETED

Evolution of Menstruation

Lead Sponsor:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Menstruation

Eligibility:

FEMALE

18-45 years

Brief Summary

This study examines gene expression and gene regulation in the uterine lining during menses in women, for evolutionary comparison with other primates which do or do not menstruate. Samples will be obt...

Detailed Description

Menstruation corresponds to the shedding of the uterine lining when fecundation has not occurred. This is a recent evolutionary innovation in primates, and the cellular and genetic changes that led to...

Eligibility Criteria

Inclusion

  • having regular periods
  • being comfortable using silicone menstrual hygiene devices ("cup")
  • having giving consent in writing

Exclusion

  • use of an internal contraception method (hormone or non-hormone based) during or within three months before the study
  • pregnancy during or within three months before the study
  • amenorrhea (absent periods) during or within three months before the study
  • gynaecological intervention or surgery within three months before the study
  • hormonal treatment during or within three months before the study
  • absence of written consent
  • breastfeeding
  • medical treatment during the study
  • low (\< 18.5) or high (\> 30) body mass index (BMI)

Key Trial Info

Start Date :

October 27 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 27 2025

Estimated Enrollment :

21 Patients enrolled

Trial Details

Trial ID

NCT04085835

Start Date

October 27 2020

End Date

April 27 2025

Last Update

October 6 2025

Active Locations (1)

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Institut de Biologie de l'Ecole Normale Superieure

Paris, Île-de-France Region, France, 75005