Status:
COMPLETED
Transcranial Direct Current Stimulation (tDCS) in the Treatment of Drug-naïve Obsessive-compulsive Disorder(OCD)
Lead Sponsor:
Shanghai Mental Health Center
Conditions:
Obsessive-Compulsive Disorder
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
This study will evaluate the possible therapeutic effects of Transcranial Direct Current Stimulation (tDCS) in drug-naïve obsessive-compulsive disorder (OCD) patients, and the underlying neural mechan...
Detailed Description
The purpose of this study is to examine the efficacy of tDCS over orbitofrontal cortex (OFC) in treatment of drug-naïve OCD patients. 60 drug-naïve OCD patients will be randomized into two groups (i.e...
Eligibility Criteria
Inclusion
- age: 18-50 years old;
- DSM-5 criteria for OCD;
- Y-BOCS total score \> or = 16, discontinued medication for at least 8 weeks before tDCS stimulation.
- \>or＝9 years education
Exclusion
- Any axis I psychiatric disorder comorbidity
- The inability to receive tDCS because of metallic implants, or history of seizures，or 3.history of head injury, or history of neurosurgery.
- Participants with claustrophobic, heart pacemaker, mechanical heart valve, mechanical implant such as an aneurysm clip, hip replacement, or any other pieces of metal that have accidentally entered their body.
- Any current significant medical condition.
- serious suicide risk
Key Trial Info
Start Date :
November 5 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2024
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT04086446
Start Date
November 5 2019
End Date
December 30 2024
Last Update
May 15 2025
Active Locations (1)
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1
Shanghai Mental Health Center
Shanghai, Shanghai Municipality, China, 200030