Status:

UNKNOWN

PET/MRI Study on the Neurological Mechanism of rTMS Treatment for Heroin Addiction

Lead Sponsor:

Tang-Du Hospital

Conditions:

Heroin Addiction

Relapse

Eligibility:

All Genders

25-55 years

Phase:

NA

Brief Summary

Heroin addiction is a serious problem and the relapse rate of existing treatment methods is extremely high. Recently, international journals such as Science reported that repetitive transcranial magne...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Heroin-dependent Participants:
  • Clinical diagnosis of heroin addiction
  • Have been receiving treatment in a methadone maintenance treatment program for no less than 6 months
  • have been on a stable dose for at least 1 month before entering the study
  • Right-handed
  • Inclusion Criteria for Healthy Control Participants:
  • Clinical diagnosis of Healthy Control
  • Right-handed
  • Exclusion Criteria for all Participants:
  • Current or past psychiatric illness other than heroin and nicotine dependence
  • Neurological signs and/or history of neurological disease
  • History of head trauma
  • History of cardiovascular or endocrine disease
  • Current medical illness or recent medicine use
  • Presence of magnetically active objects in the body
  • Claustrophobia or any other medical condition that would preclude the participant from lying in the PET/MRI scanner for approximately 40 min.

Exclusion

    Key Trial Info

    Start Date :

    June 1 2019

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    July 1 2022

    Estimated Enrollment :

    90 Patients enrolled

    Trial Details

    Trial ID

    NCT04086459

    Start Date

    June 1 2019

    End Date

    July 1 2022

    Last Update

    January 22 2021

    Active Locations (1)

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    Tangdu Hospital

    Xi'an, Shaanxi, China, 710038