Status:
COMPLETED
Assessment of Nociceptive Processing Among Patients With Temporo-mandibular Disorders
Lead Sponsor:
Université Catholique de Louvain
Conditions:
Temporomandibular Disorder
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
This case control study will investigate the physiological effect of nociceptive input in individuals with temporomandibular disorders. To do so, the investigators will compare the development of seco...
Detailed Description
This control study is designed to compare the development of secondary hyperalgesia following high frequency electrical stimulation (HFS) of skin nociceptors in the forearms in individuals with chroni...
Eligibility Criteria
Inclusion
- Inclusion Criteria for healthy controls:
- Females aged between 18 and 50 years.
- BMI between 17 and 30.
- Ability to provide written informed consent.
- Exclusion Criteria for healthy controls:
- Evidence of psychiatric/inflammatory/neurological or metabolic comorbidities on direct questioning as this study is meant to focus on musculoskeletal disorders.
- Evidence of skin alteration on the volar forearms that may interfere with HFS.
- Any substance abuse, or the use of antidepressant or neuroleptic medication as these may interfere with the psychophysical examination.
- Any painful musculoskeletal disorder.
- Lack of dental check-ups during the last 12 months.
- Inclusion Criteria for the TMD group:
- Females aged between 18 and 50 years.
- BMI between 17 and 30.
- Ability to provide written informed consent.
- Chronic TMD (for at least 3 months) as a main complain (according to the DC/TMD), with an average of at least 3/10 on a pain numerical rating scale during the past month in the orofacial region.
- Exclusion Criteria for the TMD group:
- Evidence of psychiatric/inflammatory/neurological or metabolic comorbidities on direct questioning as this study is meant to focus on musculoskeletal disorders.
- Evidence of skin alteration on the volar forearms that may interfere with HFS.
- Any substance abuse, or the use of antidepressant or neuroleptic medication as these may interfere with the psychophysical examination.
- Lack of dental check-ups during the last 12 months
Exclusion
Key Trial Info
Start Date :
January 11 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 29 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04086732
Start Date
January 11 2021
End Date
March 29 2022
Last Update
April 7 2022
Active Locations (1)
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1
Cliniques universitaires St-Luc
Brussels, Belgium, 1200