Status:
COMPLETED
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Lead Sponsor:
Andrews Research & Education Foundation
Conditions:
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Rupture
Eligibility:
All Genders
14-40 years
Phase:
PHASE2
Brief Summary
A potential long-term consequence of anterior cruciate ligament injuries is the development of post-traumatic osteoarthritis in the years following injury. There are no curative treatments for osteoar...
Detailed Description
A non-surgical treatment option for the management of osteoarthritis include injectables such as corticosteroids and platelet rich plasma. These injectables work by positively affecting cartilage cell...
Eligibility Criteria
Inclusion
- No history of previous traumatic ipsilateral knee injury
- Bone bruise visualized on MRI
- No clinical evidence of posterior cruciate ligament injury with no more than grade 1 medial or lateral collateral ligament injury
Exclusion
- Patients without a palpable knee effusion
- An injury occurring more than 10 days before enrollment
- Previous ipsilateral knee surgery
- Intra-articular cortisone or platelet rich plasma injection into either knee within 3 months of injury
- Participation in another clinical drug trial within the 4 weeks before injury
- A history of any inflammatory disease or immune-comprised
Key Trial Info
Start Date :
September 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 21 2023
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04088227
Start Date
September 12 2019
End Date
April 21 2023
Last Update
February 17 2025
Active Locations (1)
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1
Andrews Institute for Orthopaedics & Sports Medicine
Gulf Breeze, Florida, United States, 32561