Status:
COMPLETED
EAdi as a Predictor of Successful Extubation in Patients With Traumatic Cervical Spinal Cord Injury
Lead Sponsor:
Southeast University, China
Conditions:
Traumatic Cervical Spinal Cord Injury (CSCI)
Eligibility:
All Genders
18+ years
Brief Summary
Esophageal recordings of diaphragm electrical activity (EAdi) made it possible to monitor respiratory drive and the subsequent phrenic nerve conduction and respiratory neuromuscular function continuou...
Detailed Description
A retrospective cohort study enrolled adult traumatic CSCI patients who underwent mechanical ventilation and admitted to the intensive care unit (ICU) of Zhongda hospital form June 2014 to July 2018. ...
Eligibility Criteria
Inclusion
- age 18 years or older
- Traumatic CSCI patients with a neurologic level of injury of C1 to C8 by the American Spinal Injury Association (ASIA) standard impairment scale grade A to D
- patients with mechanical ventilation due to acute respiratory failure and admit to ICU
- with dedicated nasogastric tube with nine electrodes that allow to continuously measure diaphragm electrical activity (EAdi catheter, Maquet, Solna, Sweden) in position.
Exclusion
- tracheostomy before ICU admission
- withhold or withdraw life sustaining treatment due to other serious organ injury
- can't complete instructional actions,
- death occurred within 7 days after injury
- postoperative MV was a direct result of surgery and had duration of less than 24 hours postoperatively.
- EAdi data not available
Key Trial Info
Start Date :
June 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 30 2023
Estimated Enrollment :
107 Patients enrolled
Trial Details
Trial ID
NCT04089956
Start Date
June 1 2014
End Date
April 30 2023
Last Update
June 27 2023
Active Locations (1)
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1
Ling Liu
Nanjing, Jiangsu, China, 210009