Status:
RECRUITING
Antibiotic-induced Disruption of the Microbiota
Lead Sponsor:
University of Fribourg
Conditions:
Microbiota
Antibiotic Disruption
Eligibility:
All Genders
1-2 years
Brief Summary
The use of antibiotics causes profound changes in the microbiota. However, the magnitude of the effect of intrapartum and early-life antibiotics on the breast milk and the infant oral and intestinal m...
Detailed Description
In this prospective cohort study, the investigators will determine the effect of (i) intrapartum antibiotics on the composition of the breast milk, and the infant oral and intestinal microbiota and an...
Eligibility Criteria
Inclusion
- healthy infants
- term infants (\> 37 weeks of gestation)
Exclusion
- maternal HIV infection
- maternal hepatitis B or C infection
- antibiotics in the third trimester of pregnancy
- intake of probiotics during pregnancy
- infants with the low birth weight \<2500 g
- infants with congenital abnormality
Key Trial Info
Start Date :
January 25 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT04091282
Start Date
January 25 2020
End Date
December 30 2025
Last Update
April 11 2024
Active Locations (1)
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1
Hopital cantonal Fribourg
Fribourg, Switzerland, 1700