Status:
COMPLETED
Assessment of LV/RV S and SR Before and After Percutaneous Closure of ASDs
Lead Sponsor:
Ayman khairy Mohamed
Conditions:
Atrial Septal Defect, Secundum Type
Eligibility:
All Genders
11+ years
Brief Summary
The effect of Atrial Septal Defect (ASD) closure by using larger devices on the improvement in biventricular function remains an area of active research. Therefore, the aim of the current study is to ...
Detailed Description
In most echocardiographic studies, left ventricle (LV) systolic function was normal in the patients with ASD and only a few cases had a reduced LV ejection fraction with severe right ventricle (RV) vo...
Eligibility Criteria
Inclusion
- All ASD patients who have been already selected and suitable for intervention before the starting time of the study. The criteria for ASD intervention are either haemodynamically significant shunt fraction (Qp/Qs \> 1.5) or echocardiographic signs of right heart dilation or RV volume overload and pulmonary hypertension related symptoms.
Exclusion
- Patients with a large stretched Secundum ASD ≥ 36 mm, those with insufficient ASD rims (except the aortic rim), sinus venosus or primum type ASD, irreversible pulmonary hypertension, other associated structural heart diseases, coronary artery disease, LV systolic dysfunction, atrial fibrillation, or hypertension.
Key Trial Info
Start Date :
January 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04091919
Start Date
January 1 2019
End Date
December 30 2020
Last Update
July 15 2021
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Assiut University Hospital
Asyut, Egypt, 71515
2
Ain Shams University Hospital
Cairo, Egypt, 1181