Status:

UNKNOWN

FoxO3a and PU.1 in Acute Lymphoblastic Leukemia

Lead Sponsor:

Assiut University

Conditions:

Acute Lymphoblastic Leukemia

Eligibility:

All Genders

2-17 years

Brief Summary

Acute Lymphoblastic Leukemia (ALL) is one of the four major types of leukemia which is common in both children and adolescents; however, it is the most common pediatric malignancy diagnosed in childre...

Detailed Description

Proto-oncogenes and tumor suppressor genes are the most important genes involved in leukemogenesis , which their alterations disrupt normal regulatory processes such as self-renewal, proliferation, di...

Eligibility Criteria

Inclusion

  • children aged 2-17 years and diagnosed as new cases of acute lymphoblastic leukemia

Exclusion

  • age more than 17 years
  • presence of other hematological disorders, history of other malignancies ,or relapsed ALL
  • patients under chemotherapy or radiotherapy

Key Trial Info

Start Date :

August 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2024

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT04092348

Start Date

August 1 2023

End Date

December 30 2024

Last Update

February 8 2023

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