Status:
COMPLETED
The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function
Lead Sponsor:
Pennington Biomedical Research Center
Conditions:
Endothelial Dysfunction
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The purpose of this study is to test if watermelon juice supplementation improves vascular dysfunction experience during hyperglycemia.
Detailed Description
The objective of this pilot study is to determine the potential for watermelon juice to attenuate the reduction postprandial endothelial function and skeletal muscle microvascular blood flow (MVBF) ex...
Eligibility Criteria
Inclusion
- Capable and willing to give written informed consent and understand inclusion and exclusion criteria.
- 18-40 years of age
- BMI between 18-29.9 kg/m2
- Willing to allow researchers to draw blood and conduct imaging (DXA) for research purposes.
Exclusion
- Evidence or self-reported history of type 1 or 2 diabetes mellitus
- Self-reported family history of type 2 diabetes (first degree relative with type 2 diabetes)
- Evidence or self-report history of deep vein thrombosis, pulmonary embolism, cardiovascular, peripheral vascular, cerebral vascular, pulmonary, or renal disease
- Allergy to watermelon
- Use of medication known to influence study outcomes, such as:
- Insulin
- Anti-diabetics (metformin)
- Corticosteroids
- Beta-blockers
- Anti-coagulates
- Use of supplements known to influence study outcomes, such as;
- Beta-alanine
- L-arginine
- L-citrulline
- Active smoking
Key Trial Info
Start Date :
September 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2020
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT04092439
Start Date
September 12 2019
End Date
March 20 2020
Last Update
July 30 2024
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808