Status:
COMPLETED
Bicycle Exercise Echocardiography to Assess Physiological Significance of Mitral Annular Calcification
Lead Sponsor:
Albert Einstein Healthcare Network
Collaborating Sponsors:
Lantheus Medical Imaging
Conditions:
Mitral Annulus Calcification
Eligibility:
All Genders
18+ years
Brief Summary
Many people develop calcium deposits in the heart as they get older. One of the common places for this to occur is the mitral annulus, the band of tissue that supports the mitral valve (one of four he...
Detailed Description
Mitral annular calcification (MAC) involves build-up of calcium in the mitral annulus, the fibro-muscular band which supports the mitral valve. The annulus aids in valve function, contracting in early...
Eligibility Criteria
Inclusion
- At least moderate mitral annular calcification as judged by a previously published semi-quantitative echocardiographic score
- Over 18 years of age
- Able to use the semi-supine exercise bicycle
- Should be able to give informed consent.
Exclusion
- Oxygen dependent lung or cardiac disease
- Moderate or greater aortic valvular disease
- Moderate or greater mitral regurgitation
- Reduced left ventricular ejection fraction, \<35%
- Any diagnosed coronary disease
- A resting mean gradient of ≥10 mmHg across the mitral valve.
Key Trial Info
Start Date :
November 7 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04093973
Start Date
November 7 2014
End Date
June 30 2022
Last Update
May 24 2023
Active Locations (1)
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1
Einstein Medical Center
Philadelphia, Pennsylvania, United States, 19141