Status:
WITHDRAWN
Evaluation of the Effect of Wismemo on Alzheimer's Dementia Patients
Lead Sponsor:
GenMont Biotech Incorporation
Collaborating Sponsors:
Chang Gung Memorial Hospital
Conditions:
Alzheimer Disease
Eligibility:
All Genders
55-95 years
Phase:
NA
Brief Summary
The present studies demonstrated that pro-inflammation, systemic oxidative stress and dysfunction in the brain-gut microbiota axis were involved in Alzheimer's disease (AD) pathogenesis. These results ...
Detailed Description
Previously studies have shown some probiotics could improve stress-related diseases such as anxiety, autism, depression and schizophrenia might be through regulating brain-gut microbiota axis, pro-infl...
Eligibility Criteria
Inclusion
- Subjects with Alzheimer's Dementia. (According to the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association diagnostic criteria (NINCDS-ADRDA) and new criteria and guidelines to diagnose Alzheimer's disease were published in 2011 by the National Institute on Aging and Alzheimer's Association)
- Subjects with administrating cholinesterase inhibitors, such as donepezil, rivastigmine, galantamine.
- Subjects in age of 55-95 years old.
Exclusion
- Subjects are mixed dementia and vascular dementia.
- Administration of probiotic dietary supplement 2 weeks before inclusion expect for yakult or yogurt.
- Participation in other clinical trials.
- Subjects with thyroid dysfunction.
- Subjects are receiving cancer drugs.
- Subjects are receiving immunosuppressant drugs.
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 11 2020
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04094129
Start Date
January 1 2020
End Date
February 11 2020
Last Update
February 13 2020
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.