Status:
TERMINATED
ICU Associated Weakness and Bedside Ultrasound Assessment
Lead Sponsor:
University of Calgary
Conditions:
Sarcopenia
ICU Acquired Weakness
Eligibility:
All Genders
18+ years
Brief Summary
ICU-associated weakness is a common experience for people following a critical illness. It is associated with important patient and system-relevant outcomes. Diagnosing ICU-associated weakness can be ...
Detailed Description
BACKGROUND Physical weakness is a common during and after critical illness. Weakness can develop for multiple reasons, but it can be generally be grouped into three overlapping categories: 1. Nervou...
Eligibility Criteria
Inclusion
- adult patients (age \> 18 years);
- admitted to the ICU with a diagnosis of sepsis, and;
- an ICU duration of stay of greater than 4 days (two allow for serial assessments of muscle strength and size).
Exclusion
- Any pre-existing diagnosis that would reasonably impact a participant's muscle bulk, strength, coordination, or ability to participate in the assessment
- Critical illness myopathy, critical illness neuropathy, and critical illness polyneuropathy diagnosed in the current ICU stay are not to be considered exclusion criteria as these diagnoses are directly related to the research question
- Delirium is not considered an exclusion criteria for this study so long as at least two strength assessments can be performed during the course of the participant's ICU stay.
- Any activity orders or movement restrictions (including medical devices such as casts or external fixation devices) that would preclude accurate motor strength assessment.
- Dressings, casts, or medical implements that would preclude or impede ultrasound assessment of tibialis anterior muscle cross-sectional area in both legs.
- Patients who are "proned" or in positions that make assessing tibialis anterior with ultrasound or physical exam impractical.
- Re-admission to ICU within the same hospital stay.
Key Trial Info
Start Date :
October 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2020
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT04095533
Start Date
October 1 2019
End Date
April 1 2020
Last Update
April 8 2020
Active Locations (1)
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1
Foothills Medical Centre
Calgary, Alberta, Canada, T2N 5A1