Status:

WITHDRAWN

Epigenetic Changes in Psychotherapy of Adolescents With Borderline Personality Pathology

Lead Sponsor:

University Hospital, Basel, Switzerland

Collaborating Sponsors:

Leading House for the Latin American Region (Seed Money Grant SMG 1730)

Conditions:

Borderline Personality Disorder (BPD)

Eligibility:

All Genders

14-18 years

Brief Summary

The link between epigenetic changes as an effect of psychotherapy has been investigated recently. Genes investigated in these studies were brain-derived neurotrophic factor (BDNF), NR3C1, FKBP51, MAOA...

Eligibility Criteria

Inclusion

  • adolescents presenting 3 or more criteria for BPD in the Structured clinical interview for the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) axis II personality disorders (SCID-II)

Exclusion

  • difficulties to understand or comply with instructions
  • psychotic disorders
  • pervasive developmental disorders
  • severe somatic or neurological disorders
  • severe and persistent substance addiction
  • elevated risk for complications related to blood sampling

Key Trial Info

Start Date :

April 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04095546

Start Date

April 1 2022

End Date

December 1 2024

Last Update

September 13 2022

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