Status:

COMPLETED

Highly Accelerated Dose-Integrated Radiotherapy in 5 Fractions in Breast Cancer

Lead Sponsor:

University Hospital, Ghent

Conditions:

Breast Cancer

Radiotherapy

Eligibility:

FEMALE

70+ years

Phase:

NA

Brief Summary

Adjuvant radiotherapy in breast cancer improves local control, also in the elderly. Hormonal therapy in hormone sensitive tumors improves results but can not substitute radiotherapy. Improved local co...

Detailed Description

Adjuvant radiotherapy in breast cancer improves local control and overall survival, also in the elderly. Hormonal therapy in hormone sensitive tumors improves results but can not substitute radiothera...

Eligibility Criteria

Inclusion

  • ≥ 70 years old
  • AND breast conserving surgery or mastectomy for breast carcinoma
  • AND multidisciplinary decision of adjuvant irradiation
  • AND absence of distant metastases
  • AND informed consent obtained, signed and dated before specific protocol procedures

Exclusion

  • Bilateral breast irradiation
  • In case of mastectomy: positive resection margin, needing boost
  • Mental condition rendering the patient unable to understand the nature, scope and possible consequences of the study
  • Patient unlikely to comply with the protocol; i.e. uncooperative attitude, inability to return for follow-up visits, and unlikely to complete the study
  • History of previous radiation treatment to the same region

Key Trial Info

Start Date :

January 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 13 2018

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04098926

Start Date

January 1 2015

End Date

July 13 2018

Last Update

September 23 2019

Active Locations (1)

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1

University Hospital - Radiotherapy Department

Ghent, Belgium, 9000