Status:

COMPLETED

Repetitive Transcranial Magnetic Stimulation and Multi-modality Aphasia Therapy for Post-stroke Non-fluent Aphasia

Lead Sponsor:

University of Calgary

Conditions:

Stroke

Aphasia, Non-fluent

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Many stroke survivors experience aphasia, a loss or impairment of language affecting the production or understanding of speech. One common type of aphasia is known as non-fluent aphasia. Patients with...

Eligibility Criteria

Inclusion

  • Isolated left middle cerebral artery (MCA) stroke within past 6 months (sub-acute) or more than 6 months ago (chronic)
  • Stroke type: Ischemic or hemorrhagic
  • Non-fluent aphasia as determined by the Western Aphasia Battery (Fluency \< 5)
  • English is first or primary language
  • Ability to follow 3-step commands

Exclusion

  • Prior stroke to the right frontal lobe
  • Current diagnosis of moderate to severe depression
  • Diagnosis of any other psychiatric condition
  • History of other neurologic disorders (e.g., epilepsy, brain tumor)
  • Contraindication to MRI or TMS (metal in the head or any implanted electrical device)
  • Has received intensive speech therapy within the past 6 months (\>8 hours per week)
  • Enrolled in another interventional study

Key Trial Info

Start Date :

April 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 24 2023

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT04102228

Start Date

April 15 2021

End Date

August 24 2023

Last Update

August 12 2024

Active Locations (1)

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1

Foothills Medical Centre

Calgary, Alberta, Canada, T2N 2T9