Status:
RECRUITING
Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)
Lead Sponsor:
University of Leeds
Collaborating Sponsors:
University of Oxford
Conditions:
Giant Cell Arteritis
Polymyalgia Rheumatica
Eligibility:
All Genders
50+ years
Brief Summary
A multi-centre observational study recruiting prospective and retrospective cohorts of patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The primary aim is to find genetic det...
Detailed Description
Giant cell arteritis (GCA), also known as temporal arteritis, is the most common form of primary systemic vasculitis, with up to 75,000 cases a year identified in the EU and US. It occurs almost exclu...
Eligibility Criteria
Inclusion
- Willing to self-identify an ethnic group, such as Caucasian, Asian, Afro-Caribbean.
- Have a firm clinical diagnosis of GCA or PMR, or (for patients identified prospectively) GCA or PMR should be more likely than any alternative explanation for the patient's symptoms.
- Able and willing to give informed consent. Patients will be 50 years of age or over, unless both biopsy-proven and a clinically classical case of GCA.
Exclusion
- • Patient unwilling or unable to give fully informed consent.
Key Trial Info
Start Date :
June 10 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2028
Estimated Enrollment :
4500 Patients enrolled
Trial Details
Trial ID
NCT04102930
Start Date
June 10 2005
End Date
March 31 2028
Last Update
March 30 2025
Active Locations (76)
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1
Queen Elizabeth The Queen Mother Hospital
Canterbury, Kent, United Kingdom, CT 1 3NG
2
Whiston Hospital
Prescot, Merseyside, United Kingdom, L35 5DR
3
Nevill Hall Hospital, Aneurin Bevan University Health Board
Abergavenny, United Kingdom
4
Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust
Aylesbury, United Kingdom