Status:
COMPLETED
Human Urinary Kallidinogenase Improve Short Term Motor Functional Outcome of Acute Ischemia Stroke Patients
Lead Sponsor:
The Second Hospital of Hebei Medical University
Conditions:
Stroke, Acute
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Acute cerebral infarction is a common type of ischemic stroke, causing brain dysfunction in patients with high morbidity and disability. With the changes in people's diet, lifestyle patterns and popul...
Detailed Description
A total of 80 AIS patients with the unilateral corticospinal tract damage who were matched for inclusion criterion were enrolled in this randomized controlled trial. The HUK group was administered wit...
Eligibility Criteria
Inclusion
- 18 years old ≤ age \<80 years old; Within 72 hours of onset; Diagnosed as acute cerebral infarction, and confirmed by magnetic resonance imaging as an acute infarct in the unilateral corticospinal tract; The patient's onset muscle strength grade \<4; No history of cerebral infarction or residual physical activity disorder; No other intracranial lesions; Patients or their legal representatives voluntarily Sign the informed consent form;
Exclusion
- Intracranial hemorrhagic disease: cerebral hemorrhage, subarachnoid hemorrhage, etc.; Transient ischemic attack; Intravenous thrombolysis and interventional thrombectomy; Serious physical illness affects limb movement before enrollment ; Apply other drugs with nutritional nerves and regeneration during the study period; Unstable vital signs, severe liver and kidney diseases or malignant tumors; Incomprehensible or incapable of obeying the research procedure or being unable to follow up due to mental illness, cognitive or emotional disorders;
Key Trial Info
Start Date :
July 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 25 2019
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04102956
Start Date
July 1 2017
End Date
August 25 2019
Last Update
March 1 2021
Active Locations (1)
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1
Second hospital of hebei medical university
Shijiazhuang, Hebei, China, 050000