Status:

RECRUITING

Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

Lead Sponsor:

Boston Children's Hospital

Conditions:

Sepsis

Eligibility:

All Genders

2-50 years

Brief Summary

In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe typ...

Eligibility Criteria

Inclusion

  • Case
  • sepsis patient in the ICU with a breathing tube
  • Control
  • scheduled for an elective surgical procedure and need preoperative blood draw or will have an intravenous catheter placed for the purpose of their surgical procedure
  • Plan to have endotracheal tube for planned procedures.

Exclusion

  • On chronic immunosuppressive drugs such as chronic corticosteroid use, or preexisting immunodeficiency diseases (oncology patients, patients with transplantation)

Key Trial Info

Start Date :

September 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT04103281

Start Date

September 1 2020

End Date

December 31 2026

Last Update

December 16 2025

Active Locations (1)

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1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115