Status:
COMPLETED
Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
Michigan State University
National Institute of Nursing Research (NINR)
Conditions:
Cardiometabolic Health
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Exposure to fine particulate matter (PM2.5) air pollution is an established risk factor for cardiovascular (CV) morbidity.
Detailed Description
This is a randomized double-blind placebo-controlled (sham filtration) crossover trial comparing the effectiveness bedroom-only portable indoor air filtration units \[AFUs\] to reduce personal PM2.5 e...
Eligibility Criteria
Inclusion
- Nonsmoker
- ≥60 years old
- residing in Carpenter Place Apartments
Exclusion
- Active cigarette smoker
- daily secondhand smoke exposure (self-report)
- any CV event (myocardial infarction, stroke, heart failure, revascularization) in the past 3 months
- unstable CV condition or risk factor (uncontrolled diabetes, class 3-4 angina or heart failure) or any medical condition that would place the participant at risk from participation or jeopardize study integrity (per investigators)
- expected overnight travel outside their apartment during the 14-week study period
- unable to provide informed consent
- lung disease requiring oxygen
- renal dialysis
- cancer receiving active treatment or chemotherapy
- severe uncontrolled high BP ≥160/100 mm Hg or SBP\<115 mm Hg.
- CV medication change in the prior month. If participants are on medications for high BP, diabetes, or a CV condition, they will need to have stable therapy during the prior month with no planned changes during the study period.
Key Trial Info
Start Date :
February 24 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2024
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04103346
Start Date
February 24 2020
End Date
November 1 2024
Last Update
December 27 2024
Active Locations (1)
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1
University of Michigan
Ann Arbor, Michigan, United States, 48103