Status:
COMPLETED
Mitochondrial Remodeling After Exercise
Lead Sponsor:
Oregon State University
Conditions:
Overweight and Obesity
Insulin Resistance
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Regulation of mitochondrial health in overweight and obese individuals may be impaired. The purpose of this study is to identify impairments in regulation of mitochondrial health within skeletal muscl...
Eligibility Criteria
Inclusion
- Age 18-45 years
- Body mass index (BMI) 18-45 kg/m2
- Sedentary (\<1 hour of planned exercise per week)
Exclusion
- Regular exercise (\>1 hour of planned exercise per week)
- Smoking, tobacco or nicotine use within the last 1-year
- Fasting glucose \>126mg/dL
- Hypertension (systolic pressure \>140 mmHg or diastolic pressure \>90 mmHg)
- Chronic metabolic or cardiovascular health conditions
- Pregnant, nursing, irregular menses or post-menopausal
- Lidocaine allergy
- Certain medications
- Physical limitations that prevent safe or successful exercise completion
- Diminished capacity for consent
Key Trial Info
Start Date :
August 23 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 3 2022
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT04103424
Start Date
August 23 2019
End Date
December 3 2022
Last Update
February 13 2024
Active Locations (1)
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1
Oregon State University
Corvallis, Oregon, United States, 97331