Status:

COMPLETED

The Effect of Dietary Nitrates on Physical Performance and Vascular Function in Chronic Kidney Disease

Lead Sponsor:

University of Delaware

Conditions:

Kidney Disease, Chronic

Endothelial Dysfunction

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to examine the effect of acute ingestion of a concentrated beetroot juice supplement on vascular function and exercise capacity in patients with moderate to severe chronic...

Detailed Description

People with Chronic Kidney Disease (CKD) are at an increased risk of cardiovascular disease. Blood vessel dysfunction and exercise intolerance are common in CKD. Blood vessel dysfunction has been show...

Eligibility Criteria

Inclusion

  • • Stage 3-5 Chronic Kidney Disease

Exclusion

  • History of cardiovascular disease
  • Current pregnancy
  • Uncontrolled hypertension
  • Uncontrolled hyperlipidemia
  • Current hormone replacement therapy
  • Current use of tobacco products
  • Current autoimmune disease
  • Current hyperkalemia
  • Diagnosis of a deep vein thrombosis (DVT) within the last 6 months

Key Trial Info

Start Date :

December 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 29 2017

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04103736

Start Date

December 1 2015

End Date

June 29 2017

Last Update

September 25 2019

Active Locations (1)

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Department of Kinesiology and Applied Physiology, University of Delaware

Newark, Delaware, United States, 19713