Status:

RECRUITING

Clinical and Imaging Cohort of Neuroinflammation Diseases in China (CLUE)

Lead Sponsor:

Beijing Tiantan Hospital

Conditions:

NMO Spectrum Disorder

MRI

Eligibility:

All Genders

16-75 years

Brief Summary

CLUE is a prospective study to determine structural and functional changes of brain and spinal cord, as well as the inflammatory environment in patients with neuroinflammatory and demyelination diseas...

Detailed Description

The study is an observational study of multi-model imaging to determine structural and functional changes of the brain, spinal cord and optic nervethe and inflammatory environment in patients with neu...

Eligibility Criteria

Inclusion

  • 16-75
  • Diagnosis of neuroinflammatory and demyelination disease
  • Availability of demographic and clinical data at the time disease onset
  • Informed written consent obtained from the patient, and/or patient's parent(s), and/or legal representative. Assent, if old enough to grant, will be obtained from all patients under the age of 16 years.

Exclusion

  • Patients for whom MRI is contra-indicated
  • Patients included in an ongoing clinical trial where the product is blinded

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT04106830

Start Date

January 1 2019

End Date

December 31 2028

Last Update

December 24 2024

Active Locations (1)

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Beijing Tiantan Hospital

Beijing, Beijing Municipality, China, 100053