Status:

COMPLETED

Taste Perception, Salivary Proteins & the Oral Microbiome

Lead Sponsor:

Rutgers University

Conditions:

Saliva Altered

Taste, Altered

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

Genetic differences in taste are believed to play an important role in food selection, especially for strong-tasting foods and beverages. The overall goal of this project is to better understand how g...

Eligibility Criteria

Inclusion

  • PROP insensitive individuals (PROP non-tasters; homozygous recessive for tas2R38 gene)
  • PROP high-sensitive individuals (PROP super-tasters; homozygous dominant for tas2R38 gene)
  • Overall healthy; good oral health and hygiene routine
  • Current on a routine checkup by a oral/dental health professional
  • Recently underwent dental/cleaning by a oral/dental health professional
  • No ongoing oral health problems
  • Agree to use intervention material as prescribed
  • Agree to refrain from using any other oral rinse material during the term of the study

Exclusion

  • PROP medium-taster individuals (heterozygous for tas2R38 gene)
  • Taste or smell dysfunction
  • Pregnant or nursing
  • Oral piercings
  • Smoking
  • Use of medications other than birth control

Key Trial Info

Start Date :

March 25 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 19 2019

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04107688

Start Date

March 25 2019

End Date

April 19 2019

Last Update

May 14 2024

Active Locations (1)

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Rutgers University, Department of Food Science

New Brunswick, New Jersey, United States, 08901