Status:
COMPLETED
Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
Lead Sponsor:
Fundacion Dexeus
Conditions:
Infertility
IVF
Eligibility:
FEMALE
36-40 years
Phase:
NA
Brief Summary
To examine whether the number of euploid embryos following ovarian stimulation with micronized progesterone is equivalent as compared with the number of embryos after ovarian stimulation with the use ...
Detailed Description
The pre-ovulatory surges of GnRH and LH are activated by increased concentrations of circulating estradiol, but ovulation is blocked when progesterone concentrations are elevated, due to a central inh...
Eligibility Criteria
Inclusion
- Infertile patients
- Age 36-40 years old
- BMI 18-30 kg/m2
- Undergoing preimplantation genetic screening cycles
- Planned to undergo at least two treatment cycles, to accumulate embryos to increase the chance of obtaining euploid embryos for transfer
- Willing to participate in the study
Exclusion
- Age\> 41
- Severe male factor requiring TESE (testicular sperm extraction)
- Low ovarian reserve (AMH \< 1.2 ng/ml)
- Administration of any other drug potentially interfering with the treatment.
Key Trial Info
Start Date :
September 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2022
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04108039
Start Date
September 25 2019
End Date
May 15 2022
Last Update
May 15 2023
Active Locations (1)
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1
Institut Universitari Dexeus
Barcelona, Catalonia, Spain, 08028