Status:
COMPLETED
Benzodiazepine Discontinuation in Opioid Agonist Therapy
Lead Sponsor:
Boston Medical Center
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Substance Use Disorders
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The proposed study is a clinical trial, designed to pilot test a Distress Tolerance-Benzodiazepine Discontinuation (DT-BD) intervention for patients on opioid agonist therapy who currently use benzodi...
Detailed Description
This study pilots a 13-week psychosocial intervention paired with a benzodiazepine taper with the aim of assisting individuals receiving OAT discontinue benzodiazepine use. All participants will recei...
Eligibility Criteria
Inclusion
- Age 18 or older
- Receiving OAT (methadone or buprenorphine) confirmed by toxicology testing for at least 90 days and on a steady dose for 2 consecutive weeks
- Regular BZD use defined by BZD use 3 or more times per week in past month by self-report and positive urine screen at time of recruitment
- Provides permission to contact current BZD prescriber if being prescribed BZDs
- Speaks English
- Wants to discontinue BZD use
Exclusion
- Pregnant, confirmed by urine pregnancy test
- Cognitive impairment, as indicated by a score of \< 23 on the Mini Mental Status Exam
- Any past month illicit opioid, barbiturate, z-drug, cocaine, unprescribed amphetamine, or synthetic cannabinoid use determined by self-report or urine drug test
- Receiving ongoing psychosocial treatment for BZD use disorder
- Uncontrolled seizure disorder (i.e. seizure in prior 90 days), or past BZD withdrawal seizure
- Current suicidality or homicidality
- Current psychotic symptoms
Key Trial Info
Start Date :
March 18 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 8 2021
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT04109118
Start Date
March 18 2021
End Date
July 8 2021
Last Update
February 11 2022
Active Locations (1)
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1
Boston Medical Center
Boston, Massachusetts, United States, 02118