Status:

UNKNOWN

Study of PbiO2 Variation by Body Temperature and Capnia in Severe Head Trauma Patients Treated With Targeted Temperature Control

Lead Sponsor:

University Hospital, Brest

Conditions:

Severe Brain Injury

Eligibility:

All Genders

15+ years

Brief Summary

Serious head trauma is a common and pathology and responsible of high morbidity and mortality. The major challenge, from the very first hours, is to limit cerebral ischemia by controlling secondary br...

Detailed Description

This is a prospective, non-interventional, mono-centric study at surgical intensive care unit at Brest medical university hospital. This study will be conducted in a reference center for the manageme...

Eligibility Criteria

Inclusion

  • age\> 15 years
  • severe traumatic brain injury defined by an initial Glasgow Coma Scale score less than 8 or neurological impairment in the first 24 hours with Glasgow less than 8,
  • brain hypertension refractory despite usual sedation and control of ACSOS (ICP\> 20mmHg for more than 15 minutes over a period of one hour)
  • Participation Agreement.

Exclusion

  • initial bilateral mydriasis
  • no information of the family
  • refusal of participation.

Key Trial Info

Start Date :

March 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2020

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04109430

Start Date

March 1 2019

End Date

March 1 2020

Last Update

September 30 2019

Active Locations (1)

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1

HUET

Brest, Brittany Region, France, 29200