Status:
UNKNOWN
Effect of a Dietary Fatty Acid Supplementation on Symptoms and Bronchial Inflammation in Patients With Asthma
Lead Sponsor:
Stefan Zielen
Conditions:
Allergic Asthma
Allergy to House Dust Mite
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The proposed study will investigate the effect of a polyunsaturated fatty acid / lipid mixture (LCPUFAs) on the clinical symptoms, bronchial inflammation and lung function in allergic asthma in a bron...
Detailed Description
Asthma is a chronic lung disease, which is characterized by recurrent obstruction, a hypersensitivity and a chronic inflammation of the airway. It is known that LCPUVAs could reduce the production of ...
Eligibility Criteria
Inclusion
- Informed consent
- Patients: aged ≥18 and 45 years
- known allergen induced asthma and HDM-Allergy
- basic lung function FVC ≥ 80%, FEV1 ≥ 75%
- decrease in FEV1 after BAP ≥ 20%
- 30% increase of NO after BAP
Exclusion
- lung function Forced vital capacity (FVC) \<80% and Forced expiratory volume in 1 second (FEV1) \<75%
- chronic diseases or infections (e.g. HIV, Tbc)
- pregnancy
- systemic corticosteroid-treatment
- inhalative corticosteroid therapy or leukotriene antagonists
- alcohol, substance or drug abuse
- current smokers
- inability to capture extend and consequences of the study
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04109534
Start Date
October 1 2019
End Date
December 30 2020
Last Update
October 1 2019
Active Locations (1)
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1
Klinik für Kinder- und Jugendmedizin Universitätsklinikum
Frankfurt am Main, Hesse, Germany, 60590