Status:
COMPLETED
DKK3 for Prognosis and Monitoring of GFR Decline in Heart Failure
Lead Sponsor:
University of Giessen
Conditions:
Heart Failure
Chronic Kidney Diseases
Eligibility:
All Genders
18+ years
Brief Summary
The individual course of chronic kidney disease (CKD) may vary, and improved methods for identifying which patients will experience estimated glomerular filtration rate (eGFR) decline are needed. Rece...
Detailed Description
The individual course of chronic kidney disease (CKD) may vary, and improved methods for identifying which patients will experience estimated glomerular filtration rate (eGFR) decline are needed. Rece...
Eligibility Criteria
Inclusion
- Outpatients ≥18 years of age with diagnosed HF or diabetes or hypertension
Exclusion
- CKD with estimated GFR \<20 ml/min/1.73 m2 (2012 CKD-EPI equation)
- CKD with extracorporeal or peritoneal ultrafiltration due to diuretic-resistant fluid overload
- active tumor disease
- inflammatory or autoimmune disease requiring systemic immunosuppressive treatment
- clinically apparent infections
- recipients of solid-organ transplants
- anticipated life expectancy of \<12 months
- likelihood of receiving advanced therapy (mechanical circulatory assist device/cardiac transplant)
- pregnancy or possibility of pregnancy in the next 12 months
Key Trial Info
Start Date :
October 14 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 6 2024
Estimated Enrollment :
290 Patients enrolled
Trial Details
Trial ID
NCT04111094
Start Date
October 14 2019
End Date
May 6 2024
Last Update
May 9 2024
Active Locations (1)
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1
University Clinic Giessen and Marburg - Campus Giessen
Giessen, Hesse, Germany, 35392