Status:
COMPLETED
Aortic Calcification and Central Blood Pressure in Patients With Chronic Kidney Disease
Lead Sponsor:
Central Jutland Regional Hospital
Conditions:
Arterial Calcification
Kidney Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Aim and background: This study will seek to identify physiological and biochemical factors explaining and predicting a higher than expected central (aortic) blood pressure (BP) in patients with chron...
Eligibility Criteria
Inclusion
- Age \>18 years
- Patient referred for planned CAG at the Department of Cardiology, Aarhus University Hospital (AUH)
- eGFR constantly either \>60 ml/min or \<60 ml/min in at least 2 separate blood-sample measurements over at least 3 months.
- Signed informed consent-form.
Exclusion
- Antihypertensive treatment changed within the last two weeks prior to the CAG.
- Severe aortic valve stenosis (\<1 cm) as central hemodynamics may be altered
- Maximum number of patients in CKD-group already reached.
- Atrial fibrillation or other cardiac arrhythmia making radial Pulse Wave Analysis (PWA) estimations impossible.
- Known significant stenosis of a. subclavia or a. brachialis
- Bilateral arteriovenous-fistula (even if one or both of these have been surgically removed) as this may significantly affect the pulse-wave form.
Key Trial Info
Start Date :
October 15 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2022
Estimated Enrollment :
185 Patients enrolled
Trial Details
Trial ID
NCT04114695
Start Date
October 15 2019
End Date
January 1 2022
Last Update
March 31 2022
Active Locations (1)
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1
Aarhus University Hospital
Aarhus, Denmark, 8200